Advanced tracking and data relay experiments study: Multimode transponder experiment equipment

Plans and implementation concepts were developed for a series of experiments utilizing a Multimode Transponder mounted in an aircraft working either through a spacecraft or directly with a ground station which would simulate a TDRSS user working through the TDRSS. The purpose of the experiments is to determine the best modulation and encoding techniques for combating RFI in discreet bands. The experiments also determine the feasibility and accuracy of range and range rate measurements with the various modulation and encoding techniques. An analysis of the Multimode Transponder and ground support equipment is presented, and the additional equipment required to perform the experiments described above is determined

Advanced tracking and data relay experiment study: Multimode transponder experiment

A series of experiments utilizing a multimode transponder mounted in an aircraft working either through a spacecraft or directly with a ground station is studied. The purpose of the experiments is to determine the best modulation and encoding techniques for combating RFI and multipath propagation and to determine the characteristics of VHF and UHF RFI in discreet bands. The experiments would also determine the feasibility and accuracy of range and range rate measurements with the various modulation and encoding techniques

TDRSS multimode transponder program. Phase 2: Equipment development

This report contains a complete description of the TDRS Multimode Transponder and its associated ground support equipment. The transponder will demonstrate candidate modulation techniques to provide the required information for the design of an eventual VHF/UHF transponder suitable for installation in a user satellite, capable of operating as part of a Tracking and Data Relay Satellite (TDRS) systems. Use of geosynchronous TDRS which can serve both low data rate users at VHF and high data rate users at other frequencies has been considered. The effects of radio frequency interference from the earth and of multipath propagation due to reflections from the earth are expected to pose problems for the TDRS system at VHF. Investigations have suggested several modulation techniques that offer promise to overcome these problems

TDRSS telecommunications study. Phase 1: Final report

A parametric analysis of the telecommunications support capability of the Tracking and Data Relay Satellite System (TDRSS) was performed. Emphasis was placed on maximizing support capability provided to the user while minimizing impact on the user spacecraft. This study evaluates the present TDRSS configuration as presented in the TDRSS Definition Phase Study Report, December 1973 to determine potential changes for improving the overall performance. In addition, it provides specifications of the user transponder equipment to be used in the TDRSS

Corporation taxes in the European Union: Slowly moving toward comprehensive business income taxation?

This paper is a substantial revision of a paper presented at the 71st Annual Congress of the International Institute of Public Finance (Dublin, 20–23 August, 2015), which was issued under the title Tackling Spillovers by Taxing Corporate Income in the European Union at Source, as CPB Discussion Paper 324 (February 2016) and as CESifo Working Paper No. 5790 (March 2016).This paper surveys and evaluates the corporation tax systems of the Member States of the European Union on the basis of a comprehensive taxonomy of actual and potential regimes, which have as their base either profits; profits, interest and royalties; or economic rents. The current regimes give rise to various instate and interstate spillovers, which violate the basic tenets—neutrality and subsidiarity—of the single market. The trade-offs between the implications of these tenets—harmonization and diversity, respectively—can be reconciled by a bottom-up strategy of strengthening source-based taxation and narrowing differences in tax rates. The strategy starts with dual income taxation, proceeds with final source withholding taxes and rate coordination, and is made complete by comprehensive business income taxation. Common base and cash flow taxation are not favored.http://link.springer.com/journal/10797am2017Economic

Product type and the risk of inhibitor development in nonsevere haemophilia A patients: a case‒control study

Inhibitor development is a major complication of treatment with factor VIII concentrates in nonsevere haemophilia A. It has been suggested that plasma-derived factor VIII (FVIII) concentrates elicit fewer inhibitors than recombinant FVIII concentrates, but studies in severe haemophilia A patients have shown conflicting results. We designed a case‒control study to investigate the clinical and genetic risk factors for inhibitor development in nonsevere haemophilia A patients. We investigated whether the type of FVIII concentrate was associated with inhibitor development in nonsevere haemophilia A patients. This nested case‒control study includes 75 inhibitor patients and 223 controls, from a source population of the INSIGHT study, including all nonsevere haemophilia A patients (FVIII:C 2–40%) that were treated with FVIII concentrates in 33 European and one Australian centre. Cases and controls were matched for date of birth and cumulative number of exposure days (CED) to FVIII concentrate. A conditional logistic regression model was used to calculate unadjusted and adjusted odds ratios. No increased risk for inhibitor development was found for any type of FVIII concentrate; either when comparing recombinant FVIII concentrates to plasma-derived FVIII concentrates (adjusted odds ratio 0·96, 95% confidence interval (CI) 0·36–2·52) or for specific types of FVIII concentrates

The development and application of a new tool to assess the adequacy of the content and timing of antenatal care

Abstract Background: Current measures of antenatal care use are limited to initiation of care and number of visits. This study aimed to describe the development and application of a tool to assess the adequacy of the content and timing of antenatal care. Methods: The Content and Timing of care in Pregnancy (CTP) tool was developed based on clinical relevance for ongoing antenatal care and recommendations in national and international guidelines. The tool reflects minimal care recommended in every pregnancy, regardless of parity or risk status. CTP measures timing of initiation of care, content of care (number of blood pressure readings, blood tests and ultrasound scans) and whether the interventions were received at an appropriate time. Antenatal care trajectories for 333 pregnant women were then described using a standard tool (the APNCU index), that measures the quantity of care only, and the new CTP tool. Both tools categorise care into 4 categories, from ‘Inadequate’ (both tools) to ‘Adequate plus’ (APNCU) or ‘Appropriate’ (CTP). Participants recorded the timing and content of their antenatal care prospectively using diaries. Analysis included an examination of similarities and differences in categorisation of care episodes between the tools. Results: According to the CTP tool, the care trajectory of 10,2% of the women was classified as inadequate, 8,4% as intermediate, 36% as sufficient and 45,3% as appropriate. The assessment of quality of care differed significantly between the two tools. Seventeen care trajectories classified as ‘Adequate’ or ‘Adequate plus’ by the APNCU were deemed ‘Inadequate’ by the CTP. This suggests that, despite a high number of visits, these women did not receive the minimal recommended content and timing of care. Conclusions: The CTP tool provides a more detailed assessment of the adequacy of antenatal care than the current standard index. However, guidelines for the content of antenatal care vary, and the tool does not at the moment grade over-use of interventions as ‘Inappropriate’. Further work needs to be done to refine the content items prior to larger scale testing of the impact of the new measure